Writing massive multi-user web-apps in Delphi?

What technologies should I pursue to be able to develop a large-scale
web-application?

I would like to develop an app similar to ICQ (the chat service), but it
would not need to connect people in real-time (just messages).  There is a
need for some AI on the back-end, so I plan to use a 3 tiered structure.

The first tier would be an app, like ICQ is.  The second tier would be
Delphi apps running at the host location.  The third tier would be an
interbase server working with the 2nd tier Delphi apps ("Application
Servers").   The AI might be off-loaded to a 4th tier, since it would be
slow (results would be queued).

Can someone throw back the right buzzwords, and I'll go buy some books on
the right subjects:
ISAPI, NSAPI, COM/DCOM, ASP, ORB, CORBA

I am familiar with 2-tier C/S, but this 3-tier stuff has caught me off
guard.

The system needs to support about 250,000 simulateous users (ideally).
More if it catches on.

(I'm assuming I can do this project with Delphi, somehow)

Thanks,

  Bil Holland
  hollandx @hotmail.com